School of Medicine - Medicine

  • Professor Neuro Oncology
  • KIM, YOUNG ZOON
CV1

Research Interest

Malignant Brain Tumor (Surgery and Chemotherapy)
Cancer Epigenetics (Histone Modification)
Cell Cycle Regulation of Cancer Biology
Metastasis of Cancer

Education

  • Ph.D (Dong-A University Graduate School)
  • B.S. (Pusan National University College of Medicine)

Experience

  • Resident Trainee (Department of Neurosurgery, Dong-A Medical Center)
  • Clinical Fellowship (Department of Neuro Oncology, National Cancer Center)
  • Faculty Instructor (Sungkyunkwan University Masan Samsung Hospital)
  • Assistant Professor (Sungkyunkwan University Samsung Changwon Hospital)
  • Associate Professor (Sungkyunkwan University Samsung Changwon Hospital)
  • Professor (Sungkyunkwan University Samsung Changwon Hospital)

Journal Articles

  • (2023)  Clinical Application of the Association between Genetic Alteration and Intraoperative Fluorescence Activity of 5-Aminolevulinic Acid during the Resection of Brain Metastasis of Lung Adenocarcinoma.  CANCERS.  16,  1
  • (2023)  Impact on Endovascular Thrombectomy for Acute Ischemic Stroke of Aortic Arch Calcification on Chest X-ray.  JOURNAL OF CLINICAL MEDICINE.  12,  19
  • (2023)  Epigenetic Regulation of the Expression of T Cell Stimulatory and Inhibitory Factors by Histone H3 Lysine Modification Enzymes and Its Prognostic Roles in Glioblastoma.  JOURNAL OF KOREAN MEDICAL SCIENCE.  38,  33
  • (2023)  Role of Neurosurgeons in the Treatment of Acute Ischemic Stroke in the Emergency Room.  JOURNAL OF KOREAN NEUROSURGICAL SOCIETY.  66,  1
  • (2022)  Nintedanib induces senolytic effect via STAT3 inhibition.  CELL DEATH & DISEASE.  13,  9
  • (2022)  Ki67 Index Is the Most Powerful Factor for Predicting the Recurrence in Atypical Meningioma : Retrospective Analysis of 99 Patients in Two Institutes.  JOURNAL OF KOREAN NEUROSURGICAL SOCIETY.  65,  4
  • (2022)  Hypo-trimethylation of Histone H3 Lysine 4 and Hyper-tri/dimethylation of Histone H3 Lysine 27 as Epigenetic Markers of Poor Prognosis in Patients with Primary Central Nervous System Lymphoma.  CANCER RESEARCH AND TREATMENT.  54,  3
  • (2022)  Continuous centrifugal microfluidics (CCM) isolates heterogeneous circulating tumor cells via full automation.  THERANOSTICS.  12,  7
  • (2022)  Impact of the Coronavirus Disease Pandemic on Patients with Head Injuries in South Korea.  JOURNAL OF KOREAN NEUROSURGICAL SOCIETY.  65,  2
  • (2022)  Association of aortic arch calcification on chest X-ray with procedural thromboembolism after coil embolization of cerebral aneurysm.  JOURNAL OF CLINICAL NEUROSCIENCE.  99,  1
  • (2022)  Effect of Antiplatelet Preparation Before Endovascular Thrombectomy for Cerebral Infarction on Procedural Thromboembolism.  TURKISH NEUROSURGERY.  32,  1
  • (2021)  Clinical Outcomes of RTOG 9310 Protocol for Primary Central Nervous System Lymphoma: Single-Center Experience with 87 Patients.  CURRENT ONCOLOGY.  28,  6
  • (2021)  Association of Aortic Arch Calcification on Chest X-ray with Procedural Thromboembolism after Mechanical Thrombectomy for Acute Ischemic Stroke.  MEDICINA-LITHUANIA.  57,  9
  • (2021)  Improving Door-To-Puncture Time in Mechanical Thrombectomy with Direct Care from a Neurointerventionalist in the Emergency Department.  WORLD NEUROSURGERY.  152,  1
  • (2021)  The Korean Society for Neuro-Oncology (KSNO) Guideline for Adult Diffuse Midline Glioma: Version 2021.1.  Brain Tumor Research and Treatment.  9,  1
  • (2021)  The Korean Society for Neuro-Oncology (KSNO) Guideline for Antiepileptic Drug Usage of Brain Tumor: Version 2021.1.  Brain Tumor Research and Treatment.  9,  1
  • (2021)  Comparative Analysis of the Patients with Spontaneous Thalamic Hemorrhage with Concurrent Intraventricular Hemorrhage and Those without Intraventricular Hemorrhage.  JOURNAL OF KOREAN MEDICAL SCIENCE.  36,  1
  • (2021)  Comparative Analysis of the Patients with Spontaneous Thalamic Hemorrhage with Concurrent Intraventricular Hemorrhage and Those without Intraventricular Hemorrhage.  JOURNAL OF KOREAN MEDICAL SCIENCE.  36,  1
  • (2020)  Epigenetic Role of Histone Lysine Methyltransferase and Demethylase on the Expression of Transcription Factors Associated with the Epithelial-to-Mesenchymal Transition of Lung Adenocarcinoma Metastasis to the Brain.  CANCERS.  12,  12
  • (2020)  Epigenetic Role of Noncoding RNAs in the Recurrence of Pituitary Adenoma after Surgical Resection.  American Journal of Biomedical Science and Research.  10,  4

Publications

  • (2017)  DNA and Histone Mehtylation as Cancer Target.  Humana Press.  Lead author

Conference Paper

  • (2022)  Local treatment for CNS metastases in the targeted therapy era.  Asian Oncology Societies (아시아종양학회) 국제학술대회.  KOREA, REPUBLIC OF
  • (2021)  Hypo-trimethylation of histone H3 lysine 4 and hyper-di/trimethylation of histone H3 lysine 27 as the epigenetic markers of poor prognosis for primary central nervous system lymphoma patients.  2021 AACR-KCA Joint Conference.  KOREA, REPUBLIC OF
  • (2021)  Clinical Outcome of RTOG 9310 protocol for Primary Central Nervous System Lymphoma; Single Center Experience of 87 patients.  2021 대한신경외과학회 추계학술대회.  KOREA, REPUBLIC OF
  • (2021)  Hypomethylation of histone H3 lysine 4 and hypermethylation of histone H3 lysine 27 as the epigenetic markers of poor prognosis for primary central nervous system lymphoma patients.  2021 대한신경외과학회 추계학술대회.  KOREA, REPUBLIC OF
  • (2021)  Systemic inflammatory biomarkers can inform and augment differential diagnosis between primary central nervous system lymphoma and high-grade glioma: correlative analysis from a prospective imaging study..  2021 대한신경외과학회 추계학술대회.  KOREA, REPUBLIC OF
  • (2021)  Hypo-trimethylation of histone H3 lysine 4 and hyper-di/trimethylation of histone H3 lysine 27 as the epigenetic markers of poor prognosis for primary central nervous system lymphoma patients.  The 30th International KOGO Annual Conferenece.  KOREA, REPUBLIC OF
  • (2021)  KSNO / NCCN / EANO GUIDELINES FOR GLIOMAS.  대한신경종양학회 추계학술대회.  KOREA, REPUBLIC OF
  • (2021)  MLL4, UTX, and EZH2 regulate the expression of transcription factors associated with the epithelial-to-mesenchymal transition of lung cancer during metastasis to the brain at posttranscriptional steps.  대한종양내과학회 정기학술대회.  KOREA, REPUBLIC OF
  • (2021)  Methylation Status of Histone 3 Lysine as Prognostic Factor for Primary Central Nervous System Lymphoma; Single Center Experience of RTOG 9310 Protocol.  대한종양내과학회 정기학술대회.  KOREA, REPUBLIC OF
  • (2021)  The Methylation Status of Histone 3 Lysine as Prognostic Factor for Primary Central Nervous System Lymphoma; Single Center Experience of RTOG 9310 Protocol.  대한뇌종양학회 정기학술대회.  KOREA, REPUBLIC OF
  • (2021)  MLL4, UTX, and EZH2 regulate the expression of transcription factors associated with the epithelial to mesenchymal transition of lung adenocarcinoma metastasis to brain by histone modification at posttranscriptional stage.  대한암학회 정기학술대회.  KOREA, REPUBLIC OF
  • (2021)  Epigenetic role of histone lysine methyltransferase & demethylase on the expression of EMT-associated transcription factors of lung cancer metastasis to brain.  대한신경외과학회 춘계학술대회.  KOREA, REPUBLIC OF
  • (2021)  MLL4, UTX, and EZH2 Regulate the Expression of Transcription Factors Associated with the Epithelial-to-Mesenchymal Transition of Lung Adenocarcinoma Metastasis to Brain by Histone Modification at Posttranscriptional Stage.  EACR-OECI Joint Conference.  EU
  • (2020)  Clinical Factors Associated with Recurrence in Atypical Meningioma: Retrospective Analysis of 99 patients in Two Institutes.  Annual Meeting of Society for Neuro Oncology.  UNITED STATES
  • (2020)  Epigenetic Regulation of Epithelial-to-Mesenchymal Transition as a Captain of Journey of Cancer from Lung to Brain.  EORTC-NCI-AACR Conference.  UNITED STATES
  • (2020)  Comparative analysis of the patients with spontaneous thalamic hemorrhage with concurrent intraventricular hemorrhage and those without intraventricular hemorrhage.  대한신경외과학회 추계학술대회.  KOREA, REPUBLIC OF
  • (2020)  Ki67 index is the most powerful factor for predicting the recurrence in atypical meningioma: Retrospective analysis of 99 patients in single center.  대한신경외과학회 추계학술대회.  KOREA, REPUBLIC OF
  • (2020)  Practical use of the new 2017 WHO classification of silent pituitary adenoma; retrospective analysis in single centre.  대한신경외과학회 추계학술대회.  KOREA, REPUBLIC OF
  • (2020)  Epigenetic Regulation of Epithelial-to-Mesenchymal Transition as a Captain of Journey of Cancer from Lung to Brain.  대한신경종양학회 추계학술대회.  KOREA, REPUBLIC OF
  • (2020)  Epigenetic role of histone lysine methyltransferase and demethylase on the expression of transcription factors associated with the epithelial-to-mesenchymal transition of lung adenocarcinoma metastasis to the brain.  생화학분자생물학회 국제학술대회.  KOREA, REPUBLIC OF